It involves demyelination and axonal loss, predominantly affecting the white matter of the posterior and lateral columns of the spinal cord, leading to subacute sensory-motor ataxia and spastic paraplegia
N., Hale, D
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Likewise, NADP(H) is a coenzyme regulating the rate of roughly 100 cellular reactions with the vast majority being regulated by the [NADPH]/[NADP + ] (Goodman et al., 2018)
[3] Nevertheless, they are part of the ATP-grasp superfamily, which consists of 21 enzymes that contain an ATP-grasp fold