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In this study, we administered metformin to mice in order to assess changes in the intestinal barrier, cell ferroptosis, microbial composition, and metabolites in a mouse model of IIRI

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Important Safety Information Contraindications: Active cancer or malignancy (use only with medical supervision) Pregnancy or breastfeeding (insufficient safety data in these populations) Known allergy to peptide compounds Severe uncontrolled medical conditions without physician oversight Monitoring recommendations: While intensive monitoring is not required as with growth hormone, baseline and periodic assessment of body composition, basic metabolic panel, and general health markers ensures optimal results and safety