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However, CNS-specific GLP-1R KO mice have normal body mass and composition whether on a chow or HFD [688], suggesting that these receptors may be necessary for the pharmacological response to GLP-1 but not the physiological control of body weight

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As a second-line treatment, neurologists suggest cognitive behavioral therapy

Side Effects & Safety Injection site reactions -- mild redness, itching (rotate sites) Water retention -- first 1-2 weeks, transient Tingling/numbness -- GH elevation effect