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Efficacy: Topicals may work on surface pigmentation, but are less effective alone

Erastin induces considerable apoptosis and reduces the growth capacity of metastatic colorectal cancer, with IC50 values 3-fold lower compared with those of sulfasalazine (SASP), which suggested that erastin is more effective compared with SASP (54)

LPCN 1144 is also being studied in a POC clinical study in potential NAFLD / NASH subjects with confirmed fatty liver by MRI-PDFF techniques

It received final passage in the Senate with a 37-0 vote

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