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However, 20% of men, who eventually had a PSA response to chemotherapy, had an initial rise in their serum PSA and the median time to PSA response was 44 days (range 2668 days), so most patients received two or more cycles of treatment before their response status could be ascertained (Tannock et al, 2004)

After washing twice with PBS, 2 M DCFH-DA was added and cells were incubated for 30 min at 37 C

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MDA, malondialdehyde

Subcutaneous administration delivers the peptide directly into the interstitial space, where it can access the lymphatic system and enter circulation with minimal degradation

Commercial products use various concentrations based on extrapolation from preclinical data rather than human optimization studies