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Given the complex interplay between sex hormones like estrogen and progesterone and GLP-1 efficacy and tolerability, an individualized approachpotentially guided by emerging AI clinical modelsis essential to optimize dosing

These findings have generated considerable scientific interest, though it is important to note that retatrutide remains under investigation and has not yet received regulatory approval for routine clinical use

On December 28, 2023, follow-up imaging upon readmission revealed tumor progression, with the mass having enlarged to 4.3 0.9 1.3 cm ( Figures 1C, D )

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