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Metabolic improvements have compounded

In people with preexisting conditions like chronic kidney disease or liver cirrhosis, high-dose IV infusion may place additional stress on these organs

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It is also used in obesity as a weight loss regimen

In a cell culture study and an animal model, genistein plus cabazitaxel (Jevtana) significantly slowed the growth of metastatic castration-resistant prostate cancer more than a control solution or either alone (Zhang 2013)