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In long-term phase 3 studies involving adults with overweight or obesity, participants treated with injectable GLP-1 medications achieved average weight reductions commonly ranging from approximately 10% to 20% of baseline body weight when treatment was maintained beyond one year

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The proposed mechanism suggests that postbiotic cell wall components interact with toll-like receptors on intestinal cells, triggering downstream signaling cascades that support GLP-1 secretion

GLP-1 receptor agonists are medications for type 2 diabetes and weight management that work by mimicking a natural intestinal hormone

Natural products and their derivatives as candidate treatments for hair greying: from drug discovery to molecular mechanisms