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Transthoracic echocardiography was conducted using a Sonos 5500 system with an 1115 MHz linear transducer

Deep sleep triggers GH release, and GH itself promotes the transition into slow-wave sleep stages

In fact, some evidence suggests that long-term calorie restriction may even increase it a bit

For most researchers with normal pituitary function, this is not a concern

That said, results are mixed overall as to how much IGF-1 may affect breast cancer risk (22)

In one study, long-term IGF-1 administration in old age animals increased neurogenesis, vascular density and glucose utilization in brain parts responsible for memory and learning [12]