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The median follow-up duration was 1 year (IQR: 0.52 years), with key findings including a median weight loss of 11.7 kg and a median BMI at the most recent follow-up of 31.2 kg/m 2 , reflecting a median reduction of 3.7 kg/m 2

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To conduct the review, a structured search was performed on SCOPUS, Medline (PubMed), and Web of Science (WOS) databases

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However, FDA scientists have already issued briefing documents recommending against adding any of these seven peptides to the approved 503A Bulks List, citing a stark absence of rigorous human clinical data to verify their safety or efficacy