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Gentiopicroside improves dss-induced ulcerative colitis and secondary liver injury in mice by enhancing the intestinal barrier and regulating the gut microbiome

Besides, elevated ROS also leads to the activation of astrocytes and microglia, along with the excessive generation of pro-inflammatory mediators (Solleiro-Villavicencio and Rivas-Arancibia 2018)

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In rodent studies, semaglutide increased the risk of medullary thyroid carcinoma and MEN 2 syndrome

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