For the mass spectrometry, the data-dependent MS 2 scan conditions were applied in both positive and negative mode: the scan range was from m/z 2501500, resolution was 60,000 for MS, and 30,000 for DDMS 2 (top 10), and the AGC target was 3E 6 for full MS and 1E 5 for DDMS 2 , allowing ions to accumulate for up to 200 ms for MS and 50 ms for MS/MS
However, the pharmacokinetic assessment and toxicological studies of spice-derived phytocompounds must be critically checked to evaluate their safety profile and to establish their potential in translational medicine
Mov Disord 6(3):212216
Source: Jastreboff et al., NEJM 2023
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Similarly, someone with bulimia nervosa could misuse a GLP-1 in the same way they might turn to self-induced vomiting, laxatives, or excessive exercise to compensate for binge eating behaviors