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identify an unexpected metabolic underlying mechanism for this disease: the lipid chaperone fatty-acid-binding protein 5 (FABP5) aggravates psoriatic inflammation by driving keratinocytes into ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation (Fig

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59 ) without clear evidence of an interaction effect, although a study exploring a genome-wide association database did identify an interaction of one risk SNP with UA 60

A Glutathione itself has been used in medical treatments for conditions such as morning sickness and pregnancy-related complications

The MG detoxification function is fulfilled by the evolutionarily conserved glyoxalase pathway (see Section 4)