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In summary, there is a pressing need for large-scale, prospective studies to determine the optimal timing for perioperative cessation of GLP-1RAs, GIP/ GLP-1RAs, and looking ahead emerging triplehormone receptor agonists [44]

Older adults, for instance, may be more sensitive to medications and may need lower doses

753 The role of lactate in chromatin modifications has been historically overlooked, but recent discoveries suggest that lactate promotes histone lactylation, potentially aiding cancer cell invasion

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OS can be overcome by reducing generation of ROS or increasing the amounts of antioxidants available