Endocrinology 149 , 36053616 (2008)
Less common but more serious side effects of GLP-1 agonists include: Pancreatitis, an inflammation of the pancreas that causes abdominal pain Gastroparesis, in which the movement of food out of the stomach is slowed or stopped Bowel obstruction, a blockage that keeps food from passing through the intestines Gallstone attacks and bile duct blockage When to See a Doctor About GLP-1 Drug Side Effects Most side effects of GLP-1 drugs are not serious
No serious adverse events have been reported in the available literature at therapeutic doses
Frontiers in Pharmacology, 12, 734045
For experiments involving caspase-3/7 staining, CellEvent Caspase-3/7 Green Detection Reagent (Thermo Scientific C10723) and CPP-CAND were added to live cells 24 h before imaging using an Eclipse Ti-U inverted microscope (NIKON)
[ Randomized controlled trial, limited recommendation ] Key question Is early intensification of pharmacologic treatment (combination therapy of different classes) more effective in improving health outcomes compared to delayed treatment intensification in people with T2DM
