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Acknowledgments The authors would like to thank all the reviewers who participated in the review and MJEditor (www.mjeditor.com) for its linguistic assistance during the preparation of this manuscript

Meniscus tears with the highest potential for healing alone or with minimal non-invasive treatment are stable incomplete tears and small tears located in a red zone

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Investigation of pH optimum and activation by SDS Spectroscopic measurements were all carried out on TECAN infinity M200 (Tecan, Salzburg, Austria) in 96 well plates