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Side effects are minimal and may include mild discomfort or bruising at the IV insertion site

Finally, rosiglitazone increased the expression of thyroid-specific differentiation markers ( in vitro study, under normoxic or hypoxic conditions, it was reported that rosiglitazone inhibited TC cell growth and increased NIS protein expression

The safety profile established in Phase 1 trials guided safety monitoring protocols for subsequent phases of development

Sarhan M, Land WG, Tonnus W, Hugo CP, Linkermann A (2018) Origin and consequences of necroinflammation

HT induces ferroptosis by inhibiting the Nrf2 signaling pathway To investigate the intrinsic mechanism of HT-induced ferroptosis in HCT116 and SW480 cells, western blot analysis was conducted, which revealed that HT induced cellular ferroptosis and was associated with inhibition of the Nrf2 pathway