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The glutathione homeostasis system mainly contains five enzymes, -glutamylcysteine synthetase and glutathione synthetase involved in glutathione biosynthesis, glutathione peroxidase and glutathione reductase involved in recycling of the GSH, and glutathione S-transferase involved in detoxification of several stressors 20,25,27

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Additionally, a meta-analysis conducted by Fereshteh Mehri explicitly highlighted a significant association between occupational silica exposure and the risk of developing RA among various worker populations [59]

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Systemic Regulation: Once in the blood, it mimics the natural hormone GLP-1: it signals the pancreas to release insulin when blood sugar levels rise, tells the liver to stop pouring out unnecessary excess sugars, and significantly delays stomach emptying to suppress intense appetite cravings and maintain prolonged fullness

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