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Although the rates of gallstone-related hospitalization were relatively low in both groups, at 1.5% per year in those on the very-low-calorie diet and 0.4% per year in those on the low-calorie diet, the results suggest that the health benefits of weight loss may be best achieved through modest calorie restriction (Johansson 2014)

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That said, the procedure is not considered extremely painful

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Due to its regenerative properties, TB-500 has garnered attention in sports medicine and scientific research, especially in the field of tissue repair and regeneration