Reported side effects in human anecdotal use are generally mild and may include: Mild nausea, particularly with oral administration Redness, itching, or irritation at the injection site Temporary dizziness or mild headache Changes in appetite or weight A significant theoretical concern revolves around its pro-angiogenic properties
There was a significant loss of Dnmt activity and rise in Tet activity in the treatment group
Neuroprotective effects of SIRT1 SIRT1 exerts a neuroprotective effect through the regulation of the expression of transcription factors including forkhead box O3 (FOXO3A), p53, E2F transcription factor 1 (E2F1), and C-terminal binding protein (CtBP) (Lu and Wang 2017)
10.1038/s41574-022-00721-3 Nat Rev Endocrinol
The precise mechanisms driving altered metabolic pathways in ME/CFS, GWS, and FM remain to be elucidated
Amsterdam: Elsevier Health Sciences (2018)