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One common oxidative DNA lesion is 8-hydroxydeoxyguanosine (8-OHdG), which results from the interaction of ROS with guanine bases [97]

However, research indicates GIP could play a role in fat metabolism, adipose regulation, and energy expenditure

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For instance, curcumin has shown potential in decreasing glycated hemoglobin and low-density lipoprotein (LDL) levels while increasing high-density lipoprotein (HDL), improving overall metabolic control in diabetes [54]

5 Mitochondrial GSH depletion sensitizes cells to BSO treatment

Healthcare professionals should provide comprehensive patient education at treatment initiation, including written instructions and, where possible, practical demonstration