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J., Seol, J., Kim, S

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Genome Res 25:10431055 Wood DE, Lu J, Langmead B (2019) Improved metagenomic analysis with kraken 2

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This scoring system has been validated in multiple murine colitis studies and reliably assesses disease severity

For example, in mice, dopamine (10 5 and 10 7 M) downregulates the suppressive activity of T regs but does not affect the D1-mediated response of T-effector cells to regulatory cell suppression, which may be mediated by ERK signaling (Kipnis et al., 2004)