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In cross-sectional studies, low circulating IGF-I levels were found to be associated with angiographically documented coronary artery disease[275] and may predict fatal ischemic heart disease[272], a significantly increased risk of ischemic stroke and congestive heart failure in elderly patients[276, 277], as well as a worse prognosis of recovery after an acute myocardial infarction[278]
[28] [29] The most common side effects include nausea, vomiting, diarrhea, abdominal pain, and constipation
The Pg group showed a marked increase in plasma TMAO, betaine, and creatinine levels, whereas no significant differences were observed in the gut TMAO level among the four groups
Without the Clostridium butyricum and Bifidobacterium infantis supporting strains, the GLP-1 stimulating effects are reduced, because the synergistic butyrate production pathway is missing
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