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Sometimes a deficiency causes neurological symptoms, such as numbness in the hands and feet, confusion, or trouble speaking or walking
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The covariates included age (modelled as a continuous variable using cubic splines with five knots at the 5th, 27.5th, 50th, 72.5th, and 95th centiles), sex, smoking status, body mass index, alcohol related disorders, and cohort entry year (2013-15, 2016-18, 2019-21)
All interventions were compared with the use of SGLT2is and GLP-1 RAs in 2019 (the latest year with available data), i.e