It's found to be very high in youth, in, in serum levels
Psychol Bull 112 , 155159 (1992)
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They often improve with consistent use as your body adjusts to the medication
Parrado et al., 2012
Other reported mechanisms include activation of FAK-paxillin complexes (which help cells migrate and attach to surfaces during wound healing), JAK-2 signaling, and ERK1/2 pathway activity (Sikiric et al., Current Neuropharmacology, 2016