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Lyophilization enhances stability and extends shelf life, making it ideal for long-term storage

Another way in which autophagy negatively regulates TBK1 stability is through the autophagy protein ATG4B, which serves as an adaptor for the recruitment of TBK1 to gamma-aminobutyric acid receptor-associated protein (GABARAP) via its LIR motif

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Peptide Signaling Context Frequently evaluated in experimental models designed to examine cellular communication and structural protein regulation mechanisms

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Several of these studies show significant benefit, although they generally fall short of providing sufficient evidence to advocate for B12 supplementation due to small study sizes, short follow-up periods and absence of placebo arms