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WADA prohibited substance BPC-157 has been on the World Anti-Doping Agency Prohibited List under category S0 (non-approved substances) since 2022 and remains on the 2025 list

BPC 157 therapy counteracted cognitive dysfunction in a novel object recognition test [171], particularly resembling a negative-like symptom [204,205,206,207]

It features two distinct structural modifications: the substitution of a Glutamic acid for an Arginine at position 3 (hence Arg3), and a 13-amino-acid extension piece at the N-terminus (hence Long)

Research has shown NNMT is overexpressed in the adipose tissue of obese individuals (Kraus et al., 2014)

Key areas of research interest include the following