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These findings support the role of androgen/AR axis in modulating the insulin responsiveness in males

10.1210/jcem.85.9.6816 J Clin Endocrinol Metab

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But in the short run, GI side effects like Nausea, vomiting, and diarrhea can leave you dehydrated, and dehydration can cause a temporary drop in kidney function that shows up as a rising creatinine and a falling eGFR