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Ilias I, Manoli I, Blackman MR, Gold PW, Alesci S

The underlying driver is chronic inflammationspecifically, dysregulated immune signaling involving TNF-, interleukins (IL-17, IL-23), and NF-B pathways

And then suddenly with, you know, being 63 years old you start going out and doing these sports again, I think that is maybe a huge component that, from what I see so far, might even be outpacing or outweighing some of the actual biological effects that we are seeing in terms of the GLP-1 medicines

Incidence of type 1 and type 2 diabetes in adults aged 30-49 years: the population-based registry in the province of Turin, Italy

The effect varies by medication, dose, and whether the drug is used for diabetes or obesity, but the overall pattern is clear

Weve done detailed studies to show how well this technology works