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Biol Chem 2009;390:191214 8

Interestingly, exposure of endothelial cells to homocysteine would accelerate the rate of cellular senescence and increase the amount of telomere length lost per population doubling, through a redox-dependent pathway (Xu et al, 2000)

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MOTS-c targets four domains

Vivo 18 , 377390 (2004)