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The potential relationship between GLP-1 receptor agonists like semaglutide and thyroid C-cell tumors has been observed in rodent studies, where dose-dependent and duration-dependent increases in thyroid C-cell tumors were noted
This consistently worsens outcomes and complicates treatment
Both intermittent dosing schedules (injections on specific days) and continuous daily administration showed benefits, suggesting some flexibility in protocol design
Splitting the dose flattens the AUC curve and lowers that peak
Please follow your physician's mixing and dosing instructions if they differ from the ones we have listed above
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