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Endothelial dysfunction and prothrombotic reprogramming Endothelial cells (ECs) exposed to NET components undergo profound functional reprogramming, shifting from physiological vascular homeostasis toward inflammationdriven endothelial injury and a procoagulant phenotype [78]

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This systems-based perspective is exactly what FMU's Functional Medicine 2.0 curriculum teaches the ability to see how every system communicates and compensates when metabolism is under stress

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