Oosterloo BC, de Feijter M, Croll PH, Baatenburg de Jong RJ, Luik AI, Goedegebure A
In planta expression allows for functional characterization of these proteins
the possible involvement of sensory neurons in the salutary effects of NaBPC157 (10 g/kg, 10 ng/kg i.p.) was studied with capsaicin which has quite distinct effects on sensory neurons: high dose administration to adult animals (125 mg/kg s.c., (subcutaneously) three months of age) or administration (50 mg/kg s.c.) to neonatal animals (seven days of age) destroys sensory fibers, whereas a low dose (500 g/kg i.p.) activates a neurotransmitter release and protective effects on the mucosa
Jin Y, et al
Source: Prkacin et al., 2001 Multi-Organ Protection: Brain, Liver, Kidney, Lung The most comprehensive study came from Gojkovic et al
BSO inhibits GSH synthesis, thus reducing cellular GSH level