Studies have indicated that hyperoside suppresses ferroptosis by activating the Nrf2 signaling pathway, resulting in significant protective effects against S-ALI in mice ( Isoginkgetin, a natural bioflavonoid with antioxidant and immunomodulatory activities, has been shown to alleviate LPS-induced ferroptosis in pulmonary epithelial cells and improve the M1/M2 polarization imbalance in LPS-stimulated macrophages via HOXA5-mediated inhibition of the TLR4/NF- signaling pathway, thereby exerting protective effects in S-ALI in BEAS-2B cells (Lu et al., 2025)
Food Chem 368:130807 Zhong L, Carere J, Mats L, Lu Z, Lu F, Zhou T (2021) Formation of glutathione patulin conjugates associated with yeast fermentation contributes to patulin reduction
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