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Comment: A few commenters expressed concern with the potential for unintended consequences related to the current structure of the measure

Abdominal visceral fat, which responds well to beta-3 adrenergic stimulation, appears particularly susceptible to the combination approach

Technical requirements for Medicare NDC entry: Format: 11-digit NDC in 5-4-2 configuration Electronic claim (837P): enter in Loop 2410, Segment LIN, with qualifier N4 Paper claim (CMS-1500): enter in Box 19 Unit of measure qualifier: UN for units, ML for milliliters, or GR for grams Quantity reported: the actual amount administered, not the full vial size Commercial payer NDC requirements work differently

Individualized Frequency Adjustments Even though the standard is 1000 mcg monthly, some might need more or less often

The primary risk is reduced effectiveness rather than toxicity

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