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To obtain a GLP-1RG s complex with good homogeneity and stability, we used the NanoBiT tethering strategy, in which the C terminus of GLP-1R was directly attached to LgBiT subunit followed by a TEV protease cleavage site and a double MBP tag
Unlike water-soluble vitamins that are readily excreted, vitamin A accumulates in hepatic stellate cells, creating a reservoir that continues releasing toxic levels even after supplementation stops
Further, despite multiple studies on the relationship between male fertility and carnitine, the underlying molecular mechanisms remain elusive
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