When patients lose 5-10% of body weight over several months of semaglutide therapy, TSH levels sometimes increase slightly, though this change is usually modest and clinically insignificant
In patients who do not respond to diet modifications or acarbose, somatostatin analogues are supported for their ability to control symptoms of both early and late dumping syndrome (statement 53)

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This minimizes cumulative temperature exposure and preserves potency for the full duration of the vial
Seven additional phase 3 trial results are expected in 2026