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Glucagon-like peptide-1 ( GLP-1 ) receptor agonists, such as semaglutide (Wegovy) or tirzepatide (Zepbound), reduce hunger and cravings, making it easier to maintain a calorie deficit during plateaus

in both approaches, cell viability was not affected in the present study

Suspected adverse reactions should be reported through the MHRA Yellow Card scheme (yellowcard.mhra.gov.uk or via the Yellow Card app), contributing to ongoing medication safety surveillance

Faraone, S

Clinical trials show that slow dose escalation reduces adverse event severity by 40-50% compared to rapid initiation protocols

The program runs from July 1, 2026 through December 31, 2027