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To prevent evidence updates from lagging behind clinical practice, this review proposes a Learning Health System (LHS) objective: iteratively updating risk stratification and decision support through continuous real-world data streams rather than relying on static conclusions

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However, -catenin deletion in the liver results in impaired liver regeneration when different doses of APAP are utilized in WT and -catenin KO mice to achieve equal liver injury (i.e., equitoxic dose strategy), and consistent overexpression of -catenin results in significant stimulation of liver regeneration [9,14]

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Grant, MD, MS, MBA, FAANS , CEO and Co-Founder, Vori Health Martin Burruano, Vice President, Pharmacy Services, Independent Health Mark T