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Common Side Effects (Both) Injection site reaction: Brief redness, mild soreness, occasional bruising

decreasing glucagon production reduces the amount of endogenous glucose produced by the liver (see Figure)

At week 36, body-weight change from baseline was 9.0 percent in the 45 milligrams group, -10.7 percent in the 90 milligrams group and 12.1 percent in the 120 milligrams group compared to -0.5 percent for the placebo group