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[13] [15] Common side effects include local reactions at the injection site, such as pain, swelling, or erythema

The agency considers many peptides to be biologics, the most complicated and potentially high-risk type of drugs, requiring extra precautions in their manufacture and storage

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Since synergy demands a higher standard than simple overlap, its evaluation requires comparisons between combinations and individual peptides, standardized injury models, and predefined evaluation criteria (migration assays, histology, collagen organization, vascular markers, inflammatory markers, and functional metrics)

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