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This guidance and any resulting expiration date extensions authorized by FDA do not apply to doxycycline available commercially or otherwise held for any other non-emergency purpose

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A detailed description of the study design, recruitment of patients, inclusion and exclusion criteria, interventions, and previous study results are presented in recent publications ( 2.1 Subjects Briefly, 60 patients with depressive disorder aged 10-18 years and 20 age- and gender-matched healthy controls were included in this randomized, blinded, prospective study

doi: 10.1038/s41577-021-00652-6 96 JamesJ

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