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When GLP-1 medications enable significant weight loss, the reduction in adipose mass directly decreases production of these pro-inflammatory molecules

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Indeed, there are a large number of human genes that possess vitamin D-response elements (VDRE) that can bind the VDR and, therefore, be responsive to calcitriol

Nutrients 11 , 705 (2019)

Impaired Ca 2+ homeostasis can affect migration, proliferation, Purkinje cell development, dendritic arborization, synapse formation, and maintenance [94]