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Simultaneously, ferrous iron (Fe 2+ ) reacts with hydrogen peroxide (H 2 O 2 ) via the Fenton reaction to generate highly reactive hydroxyl radicals (OH), which further propagate lipid peroxidation

The evidence varies by peptide

(5) In the management of diabetes (including newly diagnosed type 2 diabetes), insulin therapy should be initiated as early as possible if there is significant unexplained weight loss[1]

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