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Preliminary studies suggest that ALA may have direct anti-cancer effects, such as inhibiting cancer cell growth, inducing apoptosis (programmed cell death), and preventing angiogenesis (the formation of new blood vessels that supply tumors)
Younossi ZM, Loomba R, Rinella ME, et al
Elevated MDA levels were observed in tissues collected from patients with toxic and non-toxic multinodular goitre, accompanied by reduced activity of SOD, GPx, and selenium content compared to adjacent, healthy thyroid tissue
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Another case study reported that high-dose oral thiamine supplementation (750 mg/day) improved the symptoms of chronic cluster headache, and confirmed its role in pain modulation (21)
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