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Nitric oxide helps dilate blood vessels, allowing more oxygen and nutrients to reach the areas that need healing

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No genotoxic activity was detected across Ames test, chromosomal aberration assay, and bone micronucleus assay

In the healing of the perforated stomach in the first 15 min, there was initially elevated NOS-2 and decreased VEGFa, then elevated NOS-2 and decreased VEGFa, then elevated COX-2, NOS-1, NOS-2, NOS-3, and then elevated COX-2, NOS-2, and decreased NOS-3 gene expression [144]

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