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In contrast, oral glutathione supplementation studies have shown inconsistent results

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While the later emphasized a dose-response effect and found no role for follow-up, however, we observed no consistent dose gradient but did find that longer follow-up linked to greater improvement on self-reported symptoms (BDI only)

Safety Toxicity There have been no reports of significant adverse side effects of oral coenzyme Q 10 supplementation at doses as high as 3,000 mg/day for up to eight months (103), 1,200 mg/day for up to 16 months (65), and 600 mg/day for up to 30 months (73)