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Among incretins, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) serve as key regulators of metabolism (8), and GLP-1 receptor agonists (GLP-1RAs) have been established as first-line therapies for type 2 diabetes (T2D) and obesity (9)

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Several findings have stressed the emphasis of clinically relevant animal models to fully understand the role of cytokines in the pathogenesis of lung bacterial infection