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While debate persists regarding the optimal dietary pattern for PCOS, the Mediterranean diet (MD), characterized by its richness in unsaturated fats, low-glycemic-index carbohydrates, fiber, and antioxidants, has emerged as a promising therapeutic approach (66)

The anionic nature of superoxide and the fact that it is mostly produced in the mitochondrial matrix determine that the bulk of antioxidant defenses to neutralize superoxide and other ROS reside in the matrix

Magnesium and calcium, which are both members of the same family in the periodic table, share a homeostatic regulatory system and have the ability to physiologically conflict with one another

10.1016/j.lfs.2023.121789 101 KhanS

Jimenez-Cauhe J, Saceda-Corralo D, Rodrigues-Barata R, et al

GSH augmentation as a potential therapeutic strategy in CNS disease has been suggested for decades, 23 although repletion efforts have been hindered by inability to assess human CNS GSH concentrations in vivo and poor oral absorption of GSH