Suvorexant, for example, is a drug targeting orexin receptors, highlighting the feasibility of this approach
Dietary modifications can substantially reduce diarrhea symptoms: Eat smaller, more frequent meals rather than large portions Reduce intake of high-fat, greasy, or fried foods, which are harder to digest with delayed gastric emptying Limit foods known to trigger diarrhea, including caffeine, alcohol, artificial sweeteners, and spicy foods Increase soluble fiber intake gradually (oats, bananas, applesauce) while avoiding excessive insoluble fiber during acute symptoms Stay well-hydrated with water and electrolyte-containing beverages Symptomatic management may include over-the-counter antidiarrheal medications such as loperamide (Imodium), though patients should consult their healthcare provider before starting these agents
AFE is a complex mixture characterized by key active compounds including arctigenin, arctiin, chlorogenic acid, and caffeic acid
Excellent sources of vitamin B12 include: Meat and poultry : Beef, lamb, and chicken provide moderate amounts (23 micrograms per 100g serving)
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Drug Discovery Today 24(2):616623 [DOI] [PMC free article] [PubMed] [Google Scholar] Pugazhenthi S, Qin L, Reddy PH (2017) Common neurodegenerative pathways in obesity, diabetes, and Alzheimers disease
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